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About

Tumor Microenvironment Lab

Overview of Services

The Tumor Microenvironment (TME) Core performs multiplexed immunofluorescence/immunohistochemical (mIF/mIHC), single color IHC assays, and amplified in situ hybridization (ISH) studies using formalin-fixed paraffin-embedded (FFPE) tissue samples collected from both humans and animals. Additionally, the TME Core will also develop new antibody protocols and mIF/mIHC panels as requested. The TME Core has two Leica Biosystems Bond RX Automated Slide Stainers, four Akoya Biosciences Vectra Polaris Automated Quantitative Pathology Imaging Systems, and two Akoya Biosciences Vectra 3.0 Automated Quantitative Pathology Imaging Systems. The TME also provides access to a Hamamatsu NanoZoomer brightfield slide scanner and a Leica Microsystems LMD7 laser capture microdissection microscope. The software required for image analysis for these platforms (Indicia Labs HALO, inForm Akoya Biosciences, etc) is also be available through the Center.

 Please navigate to the request services tab and inititate a request for services through the TME.

Leadership

Janis M. Taube MD
 Robert A. Anders MD, PhD
Co-Director Co-Director

 

Location and hours of operation

Hours Location

Open 24/7

Staffed M-F 10:00am-4:00pm

CRB2-216 (Middle Door)

1551 Jefferson Street

Baltimore, MD 21287

Links and Resources

  1. TME Available Resources - IHC, ISH, and mIF stains and pricing
  2. TME Capabilities - Equipment and Facilities for Grant Submission
  3. TME Shared Information

Contacts

Name Role Phone Email Location
Logan Engle
Sr. Laboratory Manager
 
2-2197
 
lengle1@jhmi.edu
 
CRB2-216
 

Map