The Integrated Genomics Center (IGC) is a Johns Hopkins service center providing research expertise, products, and services for the study of the human genome. We strive to streamline services such as sample collection, cell line establishment, cell line authentication, cryogenic storage, DNA isolation, oligo and gene synthesis, methylation testing, both Sanger and next-gen sequencing as well as genotyping from handfuls to millions of variants. Bioinformatics support for sequencing projects is also available. The GRCF can help with project design and custom assay development for DNA and RNA based studies.
We are a part of Johns Hopkins Genomics and function as three groups: the Core Store, the Cell Center & BioBank and DNA Services. The DNA Services group encompasses the DNA Analysis Facility, the Nucleic Acid Technologies group, the High Throughput Sequencing group and the Bioinformatics group. This site is for ordering most of the services offered by the DNA Services unit. Sanger Seqeuncing and next-gen sequencing, may be ordered on our Genesifter server. The Cell Center & Biorepository and the Core Store maintain separate ordering sites.
David Mohr (High Throughput Sequencing) Email: dwmohr@jhmi.edu Phone: 667-208-7274 Location: 1812 Ashland, 2nd floor (Primarily works remotely)
General questions should be addressed to the DNA services contact point: customorders@jhmi.edu; 410-955-2836.
Other Contacts
General Lab contact - Blalock Location Email: customorders@jhmi.edu Phone: 410-955-2836
Oligo order questions - Blalock Location Email: customorders@jhmi.edu Phone: 410-955-2836
General Lab contact - PCTB location Email: faf@jhmi.edu Phone: 443-287-7948
Location and hours of operation
Location: 600 N. Wolfe St. Blalock 1004. Baltimore, MD 21287
Hours: Monday - Friday : 7am - 4:30pm
Location: 725 N. Wolfe Street, PCTB G20, Baltimore, MD 21205
Hours: Monday - Friday: 8:30am - 4:30pm
Location: 1812 Ashland St., Baltimore, MD 21205
Hours: Monday - Friday: 8 am - 4pm
Samples should be dropped off at the appropriate location or in one of our drop boxes. High Throughput Sequencing sample drop off must be arranged prior to drop-off. Please contact David Mohr.
Remote drop off locations:
Bayview: Asthma & Allergy Building 1st floor hallway, in the specifically designated mini-fridge.
Samples must be dropped off by 11 AM daily. Pickup time is dependent on Core Store staffing, but will never be before 11 AM.
CRB1: Room B02A, in the specifically designated mini-fridge.
Samples must be dropped off by 10 AM daily. Pick up time is dependent on Core Store staffing.
Homewood: Two locations
UTL: Room 384, Black, specifically designated, mini-fridge in the break room right across from the main staircase.
Croft Hall: Outside room 141. Specifically designated mini-fridge in hallway.
Samples should be in either location by 11 AM. Pick up time is dependent on Core Store staffing.
WBSB: Third floor, near the Rangos bridge.
Samples must be dropped off by 12 Noon. Pick up time is dependent on Core Store staffing.
Lock combinations are provided in order confirmation emails. You may also call 410-955-2836 for the combination.
How to Acknowledge Us:
The Integrated Genomics Center (IGC) depends in part on proper recognition in publications, by formal mention in the acknowledgment section. Please use the suggested format below for your publications and grant applications:
“……….[insert the name of the service provided here]…………. was conducted at the Integrated Genomics Center, RRID:SCR_018669, Johns Hopkins University Department of Genetic Medicine, Baltimore, MD.”
If your journal is asking for RRIDs for materials and instrumentation used in your experiments, please reach out to us.
This special process repairs highly fragmented DNA (such as from FFPE or CF DNA) so that it is usuable on any Illumina array.
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Global Diversity Array - No Pretesting (93 samples)
Full service includes:
1 Controls per plate
Study duplicates at no additional cost (one for every other plate)
Individual sample reruns in the lab for poor performance (repeated 1X)
Full data release which includes hapmap concordance, reproducibility of genotype calculations broken down by MAF bin for each sample pair, GenomeStudio project, SNP and samples tables, full SNP technical filter applied, samples reclustered on own data, final reports, PLINK file and README docs explaining the data in each directory
Inquire
Global Diversity Array - No Pretesting (94-5000)
Full service without Pretesting includes:
1 Control per plate
Study duplicates at no additional cost
Individual sample reruns in the lab for poor performance (repeated 1X)
Full data release which includes hapmap concordance, reproducibility of genotype calculations broken down by MAF bin for each sample pair, GenomeStudio project, SNP and samples tables, full SNP technical filter applied, samples reclustered on own data, final reports, PLINK file and README docs explaining the data in each directory
Inquire
Global Screening Array - No pretesting (93 Samples)
This service level includes:
Study duplicates at no additional cost
Individual sample reruns in the lab for poor performance (repeated 1X)
Full data release, which includes hapmap concordance, reproducibility of genotype calculations broken down by MAF bin for each sample pair, GenomeStudio project, SNP and samples tables, full SNP technical filter applied, samples reclustered on own data, final reports, PLINK file and README docs explaining the data in each directory
Samples will be run as submitted, with no pretesting.
Inquire
Global Screening Array - No Pretesting (94-2000)
This service level includes:
Study duplicates at no additional cost
1 control per plate
Individual sample reruns in the lab for poor performance (repeated 1X)
Full data release, which includes hapmap concordance, reproducibility of genotype calculations broken down by MAF bin for each sample pair, GenomeStudio project, SNP and samples tables, full SNP technical filter applied, samples reclustered on own data, final reports, PLINK file and README docs explaining the data in each directory
Samples will be run as submitted, with no pretesting.
Inquire
Human QC Array - no genotypes returned
This service will test your samples to see if they are suitable for running on an Illumina array.
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Mouse GIGAmuga - Full Service (84-2000 samples)
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Oxford Nanopore Library prep
Service for ONT library prep
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Oxford Nanopore Sequencing
Service for ONT sequencing.
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Taqman OpenArray Custom Chip processing Costs
The processing costs and chip costs are billed separately. This charge is for the processing costs, which vary depending on the type of chip and number of chips processed. Price shown is for 10 chips, price will be adjusted based on actual number of chips run.
Inquire
Taqman OpenArray Custom Genotyping Chips
Minimum order 10 chips, pricing will be adjusted based on the actual quote from ThermoFisher
Global Diversity Array - No Pretesting (93 samples)
Full service includes:
1 Controls per plate
Study duplicates at no additional cost (one for every other plate)
Individual sample reruns in the lab for poor performance (repeated 1X)
Full data release which includes hapmap concordance, reproducibility of genotype calculations broken down by MAF bin for each sample pair, GenomeStudio project, SNP and samples tables, full SNP technical filter applied, samples reclustered on own data, final reports, PLINK file and README docs explaining the data in each directory
Inquire
Global Diversity Array - No Pretesting (94-5000)
Full service without Pretesting includes:
1 Control per plate
Study duplicates at no additional cost
Individual sample reruns in the lab for poor performance (repeated 1X)
Full data release which includes hapmap concordance, reproducibility of genotype calculations broken down by MAF bin for each sample pair, GenomeStudio project, SNP and samples tables, full SNP technical filter applied, samples reclustered on own data, final reports, PLINK file and README docs explaining the data in each directory
Inquire
Global Screening Array - No pretesting (93 Samples)
This service level includes:
Study duplicates at no additional cost
Individual sample reruns in the lab for poor performance (repeated 1X)
Full data release, which includes hapmap concordance, reproducibility of genotype calculations broken down by MAF bin for each sample pair, GenomeStudio project, SNP and samples tables, full SNP technical filter applied, samples reclustered on own data, final reports, PLINK file and README docs explaining the data in each directory
Samples will be run as submitted, with no pretesting.
Inquire
Global Screening Array - No Pretesting (94-2000)
This service level includes:
Study duplicates at no additional cost
1 control per plate
Individual sample reruns in the lab for poor performance (repeated 1X)
Full data release, which includes hapmap concordance, reproducibility of genotype calculations broken down by MAF bin for each sample pair, GenomeStudio project, SNP and samples tables, full SNP technical filter applied, samples reclustered on own data, final reports, PLINK file and README docs explaining the data in each directory
Samples will be run as submitted, with no pretesting.
The processing costs and chip costs are billed separately. This charge is for the processing costs, which vary depending on the type of chip and number of chips processed. Price shown is for 10 chips, price will be adjusted based on actual number of chips run.
Inquire
Taqman OpenArray Custom Genotyping Chips
Minimum order 10 chips, pricing will be adjusted based on the actual quote from ThermoFisher
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